Gene
galt
- ID
- ZDB-GENE-070112-172
- Name
- galactose-1-phosphate uridylyltransferase
- Symbol
- galt Nomenclature History
- Previous Names
-
- zgc:158795 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Exhibits UDP-glucose:hexose-1-phosphate uridylyltransferase activity. Involved in galactose catabolic process via UDP-galactose. Predicted to localize to cytoplasm. Used to study galactosemia. Human ortholog(s) of this gene implicated in classic galactosemia. Orthologous to human GALT (galactose-1-phosphate uridylyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| classic galactosemia | Alliance | Galactosemia | 230400 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR019779 | Galactose-1-phosphate uridyl transferase, class I His-active site |
| Domain | IPR005849 | Galactose-1-phosphate uridyl transferase, N-terminal |
| Domain | IPR005850 | Galactose-1-phosphate uridyl transferase, C-terminal |
| Family | IPR001937 | Galactose-1-phosphate uridyl transferase, class I |
| Homologous_superfamily | IPR036265 | HIT-like superfamily |
Domain Details Per Protein
| Protein | Length | Galactose-1-phosphate uridyl transferase, class I | Galactose-1-phosphate uridyl transferase, class I His-active site | Galactose-1-phosphate uridyl transferase, C-terminal | Galactose-1-phosphate uridyl transferase, N-terminal | HIT-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z8T3
|
391 | |||||
|
UniProtKB:E9QE09
|
364 | |||||
|
UniProtKB:A0A8M9QC62
|
187 |
Interactions and Pathways
No data available
Plasmids
No data available